can you die from gout - Uric Acid Testing
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Uric Acid Testing
Definition Uric acid tests are tests that are done to measure the levels of uric acid in blood serum or in urine. Purpose
Normal results Blood test Reference values for blood uric acid vary from laboratory to laboratory but are generally found within the following range: Male: 2.1-8.5 mg/dL; female: 2.0-6.6 mg/dL. Values may be slightly higher in the elderly. We have not included any imaginary or false information on Increased Uric Acid Levels here. Everything here is true and up to the mark!
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Decreased excretion of uric acid is seen in chronic kidney disease, low thyroid, toxemia of pregnancy, and alcoholism. Patients with gout excrete less than half the uric acid in their blood as other persons. Only 10-15% of the total cases of hyperuricemia, however, are caused by gout. Using our imagination has helped us create a wonderful article on Allopurinol. Being imaginative is indeed very important when writing about Allopurinol!
Precautions Blood test Patients scheduled for a blood test for uric acid should be checked for the following medications: loop diuretics (Diamox, Bumex, Edecrin, or Lasix); ethambutol (Myambutol); vincristine (Oncovin); pyrazinamide (Tebrazid); thiazide diuretics (Naturetin, Hydrex, Diuril, Esidrix, HydroDiuril, Aquatensen, Renese, Diurese); aspirin (low doses); acetaminophen (Tylenol); ascorbic acid (vitamin C preparations); levodopa (Larodopa); or phenacetin. These drugs can affect test results. Even the beginner will get to learn more about Uric Acid Blood Test after reading this article. It is written in easy language so that everyone will be able to understand it.
The laboratory should also be notified if the patient has had recent x-ray tests requiring contrast dyes. These chemicals increase uric acid levels in urine and decrease them in blood.
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Risks Risks for the blood test are minimal, but may include slight bleeding from the puncture site, a small bruise or swelling in the area, or fainting or feeling lightheaded. Suppressing our knowledge on Purines is not our intention here. In fact, we mean to let everyone know more about Purines after reading this!
The uric acid tests are used to evaluate the blood levels of uric acid for gout and to assess uric acid levels in the urine for kidney stone formation. The urine test is used most often to monitor patients already diagnosed with kidney stones, but it can also be used to detect disorders that affect the body's production of uric acid and to help measure the level of kidney functioning. Enhancing your vocabulary is our intention with the writing of this article on Purine Metabolism. We have used new and interesting words to achieve this.
Urine test Reference values for 24-hour urinary uric acid vary from laboratory to laboratory but are generally found within the following range: 250-750 mg/24 hours. This is a dependable source of information on Uric Acid Test. All that has to be done to verify its authenticity is to read it!
Certain foods that are high in purine may increase the patient's levels of uric acid. These include kidneys, liver, sweetbreads, sardines, anchovies, and meat extracts. We have avoided adding flimsy points on Increased Uric Acid Levels, as we find that the addition of such points have no effect on Increased Uric Acid Levels.
Uric acid is a waste product that results from the breakdown of purine, a nucleic acid. (Nucleic acids are the building blocks of DNA.) Uric acid is made in the liver and excreted by the kidneys. If the liver produces too much uric acid or the kidneys excrete too little, the patient will have too much uric acid in the blood. This condition is called hyperuricemia. Supersaturated uric acid in the urine (uricosuria) can crystallize to form kidney stones that may block the tubes that lead from the kidneys to the bladder (the ureters). We have included some fresh and interesting information on Purine Metabolism. In this way, you are updated on the developments of Purine Metabolism.
Urine test Patients should be checked for the following medications before the urine test: diuretics, aspirin, pyrazinamide (Tebrazid), phenylbutazone, probenecid (Benemid), and allopurinol (Lopurin). If the patient needs to continue taking these medications, the laboratory should be notified. We cannot be blamed if you find any other article resembling the matter we have written here about Gout Purines. What we have done here is our copyright material!
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Abnormal results The critical value for the blood test is a level of uric acid higher than 12 milligrams per deciliter (about 4 ounces).
Increased production of uric acid may result from eating foods that are high in purine. Increased uric acid levels due to overproduction may also be caused by gout, by a genetic disorder of purine metabolism, or by metastatic cancer, destruction of red blood cells, leukemia, or cancer chemotherapy. It was our decision to write so much on Purine Metabolism after finding out that there is still so much to learn on Purine Metabolism.
Abnormally low uric acid levels may indicate that the patient is taking allopurinol or probenecid for treatment of gout; may be pregnant; or suffers from Wilson's disease or Fanconi's syndrome. It may take some time to comprehend the matter on Purines that we have listed here. However, it is only through it's complete comprehension would you get the right picture of Purines.
Key Terms - Fanconi's syndrome
- A rare disorder caused by vitamin D deficiency or exposure to heavy metals.
- Gout
- A metabolic disorder characterized by sudden recurring attacks of arthritis caused by deposits of crystals that build up in the joints due to abnormally high uric acid blood levels. In gout, uric acid may be overproduced, underexcreted, or both.
- Hyperuricemia
- Excessively high levels of uric acid in the blood, often producing gout.
- Purine
- A white crystalline substance that is one of the building blocks of DNA. Uric acid is produced when purine is broken down in the body.
- Uric acid
- A compound resulting from the body's breakdown of purine. It is normally present in human urine only in small amounts.
- Uricosuria
- Increased levels of uric acid in the urine.
- Wilson's disease
- A rare hereditary disease marked by the buildup of copper in the liver and brain, causing loss of kidney function.
Further Reading For Your Information Books - Laboratory Test Handbook, edited by David S. Jacobs. Cleveland, OH: Lexi-Comp Inc., 1996.
- Mosby's Diagnostic and Laboratory Test Reference, edited by Kathleen Deska Pagana and Timothy James Pagana. St. Louis: Mosby-Year Book, Inc., 1998.
- Springhouse Corporation. Handbook of Diagnostic Tests, edited by Matthew Cahill. Springhouse, PA: Springhouse Corporation, 1995.
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Description The uric acid blood test is performed on a sample of the patient's blood, withdrawn from a vein into a vacuum tube. The procedure, which is called a venipuncture, takes about five minutes. The urine test requires the patient to collect all urine voided over a 24-hour period, with the exception of the very first specimen. The patient keeps the specimen container on ice or in the refrigerator during the collection period.
Preparation The uric acid test requires either a blood or urine sample. For the blood sample, the patient should be fasting (nothing to eat or drink) for at least eight hours before the test. The urine test for uric acid requires a 24-hour urine collection. The urine test does not require the patient to fast or cut down on fluids. Some laboratories encourage patients to drink plenty of fluids during the collection period.
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